抗磷酸酪氨酸抗体 抗磷酸酪氨酸抗体畅销 抗磷酸酪氨酸抗体供应 益启供
货号:05-321
产品名称:anti-phosphotyrosine, clone 4G10
产品介绍:抗磷酸酪氨酸抗体的出现是信号转导研究中的重要事件之一。在该抗体出现之前,通过危险和耗时的放射性实验研究蛋白和酶的酪氨酰磷酸化。该抗体可以在WB, IP, IHC等实验中使用,也直接用于细胞裂解物,以检测酪氨酸磷酸化水平在各种反应中的总体变化。4G10是phosphotyrosine检测的金标抗体。
高文献引用率:引用文献超过560篇,phosphotyrosine文献引用率居首位。(数据来自CiteAb网站)
多实验验证:ICC, IHC, IP, WB
适用于所有种属。
参考文献:
Harnessing insulin- and leptin-induced oxidation of PTP1B for therapeutic development.In Nature Communications on 18 January 2018 by Krishnan, N., Bonham, C. A., et al..Molecular interactions of EphA4, growth hormone receptor, Janus kinase 2, and signal transducer and activator of transcription 5B.In PLoS ONE on 8 July 2017 by Sawada, T., Arai, D., et al..Germline mutations in ABL1 cause an autosomal dominant syndrome characterized by congenital heart defects and skeletal malformations.In Nature Genetics on 1 April 2017 by Wang, X., Charng, W. L., et al..C-Terminal Region Truncation of RELN Disrupts an Interaction with VLDLR, Causing Abnormal Development of the Cerebral Cortex and Hippocampus.In The Journal of Neuroscience on 25 January 2017 by Ha, S., Tripathi, P. P., et al..Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors.In Nature Medicine on 1 February 2016 by Du, Y., Yamaguchi, H., et al..