Atg1/ULK1抗体 Atg1/ULK1抗体畅销 Atg1/ULK1抗体供应 益启供

Atg1/ULK1抗体 Atg1/ULK1抗体畅销 Atg1/ULK1抗体供应 益启供

货号：A7481
产品名：Anti-Atg1/ULK1 antibody
产品介绍：ULK1***并磷酸化mAtg13、FIP200和ULK1自身, 从而开启自噬发生的第一步；在缺乏营养的情况下，AMPK也可以通过磷酸化ULK1***其活性, 从而进一步促进自噬。有报道称ULK1引起的自噬可以阻碍细胞生长，引起细胞死亡或凋亡。
该抗体在WB等实验中验证
可以在mouse, human (predicted), rat等种属中进行实验。
 CiteAb网站上文献引用率位居首位
国内现货
参考文献：
Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy.
In Nature Communications on 15 September 2017 by Laker, R. C., Drake, J. C., et al..
Regulation of ULK1 Expression and Autophagy by STAT1.
In The Journal of Biological Chemistry on 3 February 2017 by Goldberg, A. A., Nkengfac, B., et al..
Suppression of autophagy impedes glioblastoma development and induces senescence.
In Autophagy on 1 September 2016 by Gammoh, N., Fraser, J., et al..
Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening.
In Oncogene on 5 November 2015 by Strohecker, A. M., Joshi, S., et al..
mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival.
In The EMBO Journal on 2 September 2015 by Munson, M. J., Allen, G. F., et al..
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.
In Nature Cell Biology on 1 March 2015 by Medina, D. L., Di Paola, S., et al..